생체이용률조절연구소

연구소장 소개

학력

• •1995.03~1999.02 삼육대학교, 약학과, 학사
• •1999.03~2001.02 삼육대학교 대학원 약학과, 석사
• •2008.03~2012.08 강원대학교 약학과, 박사

경력

• •2001.2~2004.4 초당약품 ㈜, 연구소 근무; 선임연구원
• •2004.5~2008.2 ㈜ 한독약품, 연구소 근무; Project Manger
• •2013.4~2015.02 Univeristy of Mississippi; Post-Doc Researhcer
• •2015.3~2021.2 삼육대학교 약학대학 약학과 조교수
• •2021.3~ 삼육대학교 약학대학 약학과 부교수

학회 (Society)

• 1대한약학회 정회원
• 2한국약제학회 정회원

CERTIFICATION

• • License for Pharmacist in Korea, Feb. 1999

주요연구분야

• 1 고온용융압출기술(Hot Melt Extrusion Technology)을 이용한 제제화
• 2 난용성 약물의 가용화 기술
• 3 제제화를 위한 다양한 첨가제류의 처방 및 조성물 확립 기술
• 4 위장관 투과 속도 및 양의 조절 연구 기술

논문, 책, 특허

PUBLICATIONs (최근 5년)

• •Yu-Byoung Chae, Sung-Yeop Kim, Chin-Yang Kang, and Jun-Bom Park, Effect of Hydrophilic and Hydrophobic Polymers on the Sustained-release Sarpogrelate HCl from Matrix Tablets, J. Pharm. Soc. Korea 2020, 64(6), 446-453
• •Hee Jo Yoo, Se-Jung Hwang, Jeong-Hun Lee, Wang-Seo Shim, Yun-Woong Choi, Sang Min Cho, Eun Kyoung Chung*, Jun-Bom Park*, Kyung-Tae Lee*, Development and Validation of an LC-MS/MS Assay to Quantitate 2′,4′,6′-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study, Molecules 2020, 25, 4373
• •Sung-Min Choi, Sung-Hoon Lee, Chin-Yang Kang and Jun-Bom Park, Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation, Pharmaceutics, 2020, 12, 757
• •Byung-Cheol Oh, Gang Jin, Chulhun Park, Jun-Bom Park, Beom-Jin Lee, Preparation and evaluation of identifiable quick response (QR)-coded orodispersible films using 3D printer with directly feeding nozzle, International Journal of Pharmaceutics, 2020, 584, 119405
• •Ilhwan Hwang, Vanamane Renuka, Ju-Hyun Lee, Kwon-Yeon Weon, Chin-Yang Kang, Beom-Jin Lee and Jun-Bom Park, Preparation of Celecoxib Tablet by Hot Melt Extrusion Technology and Application of Process Analysis Technology to Discriminate Solubilization Effect, Pharmaceutical Development and Technology, 2020, 25(5), 525-534
• •Bhupendra Raj Giri, Eon Soo Song, Jaewook Kwon, Ju-Hyun Lee, Jun-Bom Park and Dong Wuk Kim, Fabrication of Intragastric Floating, Controlled Release 3D Printed Theophylline Tablets Using Hot-Melt Extrusion and Fused Deposition Modeling, Pharmaceutics, 2020, 12, 77
• •Dayoung Kim, Chulhun Park, Nileshkumar M. Meghani, Thao T.D. Tran, Phuong H.L. Tran, Jun-Bom Park, Beom-Jin Lee, Utilization of a fattigation platform gelatin-oleic acid sodium salt conjugate as a novel solubilizing adjuvant for poorly water-soluble drugs via self-assembly and nanonization, International Journal of Pharmaceutics, 2020, 575, 118892
• •Sung-min Choi, Yong-Koo Jeon, Ju-Hyun Lee, Chin-Yang Kang, and Jun-Bom Park, Solubility Enhancement of Poorly Water-Soluble Drugs by Hot-Melt Extrusion Technology and Effects of Surfactant on Dissolution Test, J. Pharm. Soc. Korea, 2019, 63(6), 384-389
• •Shrawani Lamichhane, Jun-Bom Park, Dong Hwan Sohn and Sangkil Lee, Customized Novel Design of 3D Printed Pregabalin Tablets for Intra-Gastric Floating and Controlled Release Using Fused Deposition Modeling, Pharmaceutics, 2019, 11, 564-577
• •Chulhun Park, Nileshkumar M. Meghani, Yongkwan Shin, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Thao Truong-Dinh Tran, Phuong Ha-Lien Tran and Beom-Jin Lee, Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility, Pharmaceutics, 2019, 11, 102-117
• •Kyu-Yeol Nama, Sang Min Cho, Youn-Woong Choi, Chulhun Park, Nileshkumar M. Meghani, Jun-Bom Park, Beom-Jin Lee, Double controlled release of highly insoluble cilostazol using surfactant- driven pH dependent and pH-independent polymeric blends and in vivo bioavailability in beagle dogs, International Journal of Pharmaceutics, 2019, 558, 284-290
• •Changmin Kang, Ju-Hyun Lee, Dong-Wook Kim, Beom-Jin Lee, and Jun-Bom Park, Preparation of Sustained Release Tablet with Minimized Usage of Glyceryl Behenate Using Post-Heating Method, AAPS PharmSciTech, 2018, 19(7), 3067-3075
• •Seung Jin Ko, Ju-Hyun Lee, Chin-Yang Kang, Jun-Bom Park, Granulation development in batch-to-batch and continuous processes from a quality by design perspective, Journal of Drug Delivery Science and Technology, 2018, 46, 34-45
• •Jun-Bom Park, Chulhun Park, Zhong Zhu Piao, Hardik H. Amin, Nilesh M. Meghani, Phuong H.L. Tran, Thao T.D. Tran, Jing-Hao Cui, Qing-Ri Cao, Euichaul Oh, Beom-Jin Lee, pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans, Journal of Drug Delivery Science and Technology, 2018, 46, 365-377
• •Nilesh M. Meghani, Hardik H. Amin, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy, International Journal of Pharmaceutics, 2018, 545, 101-112
• •Kyung-Ho Lee · Chulhun Park · Giwon Oh · Jun-Bom Park · Beom-Jin Lee, New blends of hydroxypropylmethylcellulose and Gelucire 44/14: physical property and controlled release of drugs with different solubility, Journal of Pharmaceutical Investigation, 2018, 48, 313-321
• •Namhyun Baek, Ga-Hui Oh, Chulhun Park, Thuy Thi Thanh Tran, Young Joon Park, Euichaul Oh, Hau Le, Thao T.D. Tran, Jun-Bom Park, Beom-Jin Lee, Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification. Journal of Drug Delivery Science and Technology, 2018, 43, 477-486
• •Sung-min Choi, Chin-Yang Kang, Beom Jin Lee and Jun-Bom Park, In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism. Current Drug Metabolism, 2017, 18(11), 973-982
• •Sultan Alshehri, Roshan Tiwari, Bader Alsulays, Eman Ashour, Abdullah Alshetaili, Bjad Almutairy, Jun-Bom Park, Joseph Morott, Bhupinder Sandhu, Soumyajit Majumdar & Michael A. Repka, Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques. Pharmaceutical Development and Technology, 2017, 22(6), 740-753
• •Daoqi Luo, Joo Hee Kim, Chulhun Park, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design of fixed dose combination and physicochemical characterization of enteric-coated bilayer tablet with circadian rhythmic variations containing telmisartan and pravastatin sodium. International Journal of Pharmaceutics, 2017, 523, 343-356
• •Ilhwan Hwang, Chin-Yang Kang, Jun-Bom Park, Advances in hot-melt extrusion technology toward pharmaceutical objectives. Journal of Pharmaceutical Investigation, 2017, 47, 123-132
• •Jun-Bom Park, Dong-Wook Kim, Sung-Hoon Lee, Kwon-Yeon Weon, Development of a Process Analytical Technology(PAT) method using near-infrared spectroscopy system for evaluating an active coating process for a low-dose drug. Journal of Drug Delivery Science and Technology, 2017, 39, 8-15
• •Jun-Bom Park, Beom-Jin Lee, Chin-Yang Kang, Roshan V. Tiwari, Michael A. Repka, Process analytical quality control of tailored drug release formulation prepared via hot-melt extrusion technology. Journal of Drug Delivery Science and Technology, 2017, 38, 51-58
• •Bader B. Alsulays, Vijay Kulkarni, Sultan M. Alshehri, Bjad K. Almutairy, Eman A. Ashour, Joseph T. Morott, Abdullah S. Alshetaili, Jun-Bom Park, Roshan V. Tiwari & Michael A. Repka, Preparation and evaluation of enteric coated tablets of hot melt extruded lansoprazole. Drug Development and Industrial Pharmacy, 2017, 43(5), 789-796
• •Abdullah S. Alshetaili, Bjad K. Almutairy, Roshan V. Tiwari, Joseph T. Morott, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Jun-Bom Park, Feng Zhang and Michael A Repka, Preparation and Evaluation of Hot-Melt Extruded Patient-Centric Ketoprofen Mini-tablets. Current Drug Delivery, 2016, 13(5), 730-741
• •Eman A. Ashour, Vijay Kulkarni, Bjad Almutairy, Jun-Bom Park, Sejal Shah, Soumyajit Majumdar, Michael A. Repka, Influence of Pressurized Carbon Dioxide on Ketoprofen-Incorporated Hot-Melt Extruded Low Molecular Weight Hydroxypropylcellulose. Drug Development and Industrial Pharmacy, 2016, 42 (1), 123-130

책

• •이범진, 손동환, 한효경, 오경택, 박준범, 김성원, 최연웅, 장희철, 김병조, 박상욱, 글로벌 개량신약 연구개발과 질환별 사업화전략. 신일서적. 2020.
• •이범진, 전인구, 한효경, 박준범, 임지성, 염류의약품 물성과 선택 및 응용. 신일북스 (역자). 2013.
• •Jun-Bom Park and Beom-jin Lee, Emerging oral controlled-release technology for optimal therapy. Future Science, 2013, Nov. 40-53.

특허

• •Hemlata Patil, Vijay Kulkarni, Jun-Bom Park, Soumyajit Majumdar, Michael A. Repka, Systems and Methods for Preparing Lipid Nanoparticles.2014 # USSN 61/969,444.
• •박준범, 최성민, 생리학적 체내 동태 연구 모델링을 이용한 약제학적 조성물의 제조 방법, 10-2114550
• •박준범, 강창민, 친수성 약물을 포함하는 서방성 제제의 제조 방법, 2018, 제 10-1881749 호.
• •박준범, 강진양, 반복 고온용융 압출 성형된 약제학적 조성물의 제조 방법 및 이에 의해 제조된 약제학적 조성물, 2017, 제 10-1801476 호.
• •박준범, 이범진, 고온용융 압출을 이용한 저함량 약제학적 조성물의 제조방법, 2013, 제 10-1390946 호.